CHEMBL234650


SMILES CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)Cc3ccccc3)CC2)CC1
InChIKey OCDNDDLEORDHLQ-RQNOJGIXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 471.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.7 6.7 6.7 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.41 8.41 8.41 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.92 7.92 7.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.15 7.15 7.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database