CHEMBL2347236


SMILES C[C@H]1C2Cc3ccc(C(=O)NCCc4ccc(-c5cccnc5)cc4)cc3[C@@]1(C)CCN2CC1CC1
InChIKey IGZOVVQZHKLAFJ-WTBOZYSNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 479.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.09 8.09 8.09 ChEMBL
κ OPRK Human Opioid A pKi 8.66 8.66 8.66 ChEMBL
μ OPRM Human Opioid A pKi 10.19 10.19 10.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 7.72 7.72 7.72 ChEMBL
μ OPRM Human Opioid A pIC50 6.96 6.96 6.96 ChEMBL
μ OPRM Human Opioid A pEC50 9.07 9.07 9.07 ChEMBL