INCB-38579


SMILES CN1CCN(CC1)C1=CC(=NC(N1)N)c1ccc2c(c1)CN(CC2)C(=O)CCC1CCCC1
InChIKey JZAGLPUCLXBELH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 450.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.0 5.0 5.0 Guide to Pharmacology
H2 HRH2 Human Histamine A pKi 5.3 5.3 5.3 Guide to Pharmacology
H3 HRH3 Human Histamine A pKi 6.39 6.39 6.39 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 8.3 8.3 8.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database