CHEMBL2159487


SMILES CC(C)c1ccccc1OCCN1CC[C@@H](NS(=O)(=O)c2ccc(Cl)s2)C1
InChIKey WIMXOLDVKJDYQI-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 428.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database