CHEMBL236475


SMILES CNCc1cc(C#CCCN2CCOCC2)ccc1Oc1ccc(Cl)cc1
InChIKey AGFIIERRTNLUMS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKd 7.97 7.97 7.97 ChEMBL
H3 HRH3 Human Histamine A pKi 8.15 8.15 8.15 ChEMBL
H3 HRH3 Human Histamine A pKi 8.15 8.15 8.15 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database