CHEMBL236521


SMILES Cc1ccc(N2CCN(C(=O)[C@@H](Cc3ccc(Cl)cc3Cl)N3CCCC3=O)CC2)c([C@H](CC(C)C)NC(=O)CCN(C)C)c1
InChIKey OLLQZYNQBYGVCQ-IGYGKHONSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 643.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.08 5.08 5.08 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.28 6.28 6.28 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.09 6.09 6.09 ChEMBL
MC4 MC4R Human Melanocortin A pKi 9.22 9.23 9.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 7.72 7.72 7.72 ChEMBL