GPCRdb

CHEMBL237394

Agent/drug
Bioactivity

CHEMBL237394

SMILES	CCOc1ccc(-n2ncc(-c3ccc4cc(CCN5CCC[C@H]5C)ccc4n3)c2C)nn1
InChIKey	JBAFEJCXHMAIBL-GOSISDBHSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	0
Rotatable bonds	7
Molecular weight (Da)	442.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Rat	Histamine	A	pKi	9.00	9.23	9.31	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	9.70	9.72	9.73	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Rat	Histamine	A	pEC50	9.13	9.13	9.13	ChEMBL
H₃	HRH3	Human	Histamine	A	pEC50	9.23	9.23	9.23	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL237394

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.