kisspeptin-10


SMILES None
InChIKey RITKWYDZSSQNJI-INXYWQKQSA-N
Sequence YNWNSFGLRF

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
kisspeptin KISSR Human Kisspeptin A pKi 8.6 9.5 10.4 Guide to Pharmacology
kisspeptin KISSR Human Kisspeptin A pKd 8.7 8.7 8.7 Guide to Pharmacology
kisspeptin KISSR Rat Kisspeptin A pKi 8.8 8.8 8.8 Guide to Pharmacology
kisspeptin KISSR Human Kisspeptin A pKi 8.89 9.99 10.46 ChEMBL
kisspeptin KISSR Rat Kisspeptin A pKi 10.06 10.15 10.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pIC50 8.33 8.33 8.33 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pIC50 7.12 7.12 7.12 ChEMBL
kisspeptin KISSR Human Kisspeptin A pEC50 7.76 9.43 10.31 ChEMBL
kisspeptin KISSR Human Kisspeptin A pIC50 5.07 8.81 10.15 ChEMBL
kisspeptin KISSR Rat Kisspeptin A pEC50 8.38 8.38 8.38 ChEMBL
kisspeptin KISSR Rat Kisspeptin A pIC50 9.96 9.96 9.96 ChEMBL