CHEMBL238401


SMILES CCN([C@H]1CC[C@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1)S(=O)(=O)c1ccc(OC)c(OC)c1
InChIKey LVRHAAKFXRNPFH-RQNOJGIXSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 545.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.96 6.96 6.96 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.64 7.64 7.64 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.17 8.17 8.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.57 8.57 8.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database