kynurenic acid


SMILES OC(=O)c1cc(=O)c2c([nH]1)cccc2
InChIKey HCZHHEIFKROPDY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 189.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Mouse A orphans A pEC50 4.96 4.96 4.96 Guide to Pharmacology
GPR35 Q33BM1 Rat A orphans A pEC50 5.15 5.15 5.15 Guide to Pharmacology
GPR35 Q33BM1 Rat A orphans A pEC50 4.18 4.18 4.18 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 4.41 4.41 4.41 ChEMBL
GPR35 GPR35 Human A orphans A pIC50 4.41 4.41 4.41 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.75 7.75 7.75 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 3.9 4.16 4.41 Guide to Pharmacology