L-152,804


SMILES OC1=C(C(=O)CC(C1)(C)C)C1C2=C(Oc3c1cccc3)CC(CC2=O)(C)C
InChIKey CCJIUBMPDVWYLU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y5 NPY5R Human Neuropeptide Y A pKi 7.6 7.6 7.6 Guide to Pharmacology
Y5 NPY5R Human Neuropeptide Y A pKi 7.48 7.48 7.48 ChEMBL
Y5 NPY5R Rat Neuropeptide Y A pKi 7.5 7.5 7.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y5 NPY5R Human Neuropeptide Y A pIC50 7.21 7.21 7.21 ChEMBL