L-803,087


SMILES COC(=O)[C@@H](NC(=O)CCCc1c([nH]c2c1cc(F)cc2F)c1ccccc1)CCCN=C(N)N
InChIKey OPNMQSFIGUSHDH-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST4 SSR4 Human Somatostatin A pKi 9.2 9.2 9.2 Guide to Pharmacology
SST4 SSR4 Human Somatostatin A pKi 9.15 9.15 9.15 ChEMBL
SST2 SSR2 Human Somatostatin A pKi 5.33 5.33 5.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST4 SSR4 Human Somatostatin A pIC50 8.38 8.38 8.38 ChEMBL