CHEMBL2205811


SMILES COc1cccc(CCN2C3C4C5CC6C7C5C3C7C2(O)C64)c1
InChIKey ZKOQRCXMSDAJIR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.25 6.25 6.25 ChEMBL
H2 HRH2 Human Histamine A pKi 6.02 6.02 6.02 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.01 6.01 6.01 ChEMBL
H1 HRH1 Human Histamine A pKi 5.05 5.05 5.05 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.76 5.76 5.76 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.53 5.53 5.53 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.91 5.91 5.91 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.65 5.65 5.65 ChEMBL
κ OPRK Human Opioid A pKi 5.85 5.85 5.85 ChEMBL
μ OPRM Human Opioid A pKi 5.27 5.27 5.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database