GPCRdb

CHEMBL2387310

Agent/drug
Bioactivity

CHEMBL2387310

SMILES	CCN(CC)CCOc1ccc(NC(=S)Nc2ccc(OCC(C)C)cc2)cc1
InChIKey	HSQYVRJHKHVEKA-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	11
Molecular weight (Da)	415.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	Q865E1	Rhesus macaque	Histamine	A	pKi	7.80	7.80	7.80	ChEMBL
H₃	HRH3	Rat	Histamine	A	pKi	7.40	7.40	7.40	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	7.78	7.78	7.78	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pIC50	9.22	9.22	9.22	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL2387310

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.