GPCRdb

CHEMBL238833

Agent/drug
Bioactivity

CHEMBL238833

SMILES	COCn1c(=O)n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c2ccccc21
InChIKey	HODPFCFYQOZXPB-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	0
Rotatable bonds	10
Molecular weight (Da)	481.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	5.70	5.80	5.90	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	6.81	6.92	7.03	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	6.71	7.04	7.24	ChEMBL
NOP	OPRX	Human	Opioid	A	pKi	6.82	7.91	8.52	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NOP	OPRX	Human	Opioid	A	pIC50	7.09	7.33	7.57	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL238833

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.