CHEMBL2207637


SMILES COc1ccccc1N1CCN(Cc2cc(CN(C)C)c3cccccc2-3)CC1
InChIKey HRHSURDPAJFNRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.35 5.35 5.35 ChEMBL
H2 HRH2 Human Histamine A pKi 5.5 5.5 5.5 ChEMBL
H1 HRH1 Human Histamine A pKi 5.58 5.58 5.58 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.82 8.82 8.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.41 6.41 6.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.76 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database