GPCRdb

CHEMBL2397389

Agent/drug
Bioactivity

CHEMBL2397389

SMILES	C#CC1=CC[C@H](N(CCC)CCCCNC(=O)c2ccc(-c3ccccc3)cc2)CC1
InChIKey	PWZPBZQTTHOCIS-MHZLTWQESA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	10
Molecular weight (Da)	414.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	4.55	4.55	4.55	ChEMBL
D₁	DRD1	Pig	Dopamine	A	pKi	6.52	6.52	6.52	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	4.75	4.75	4.75	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.75	8.17	9.22	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.37	9.14	9.92	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.22	7.73	8.24	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	5.62	6.66	7.26	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL2397389

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.