L-tryptophan


SMILES OC(=O)[C@H](Cc1c[nH]c2c1cccc2)N
InChIKey QIVBCDIJIAJPQS-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 204.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7DTU 7M3E 7DTV 7DD6 7DD5 7M3F 7DD7 7M3G

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR139 GP139 Human A orphans A pKi 3.13 3.13 3.13 Guide to Pharmacology
CaS CASR Human Calcium-sensing C pKd 2.6 3.5 4.4 Guide to Pharmacology
CaS CASR Human Calcium-sensing C pKd 8.36 8.36 8.36 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR139 GP139 Human A orphans A pEC50 3.66 3.66 3.66 Guide to Pharmacology
GPR139 GP139 Human A orphans A pIC50 4.59 4.59 4.59 Guide to Pharmacology
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL
GPR139 GP139 Human A orphans A pIC50 8.34 8.34 8.34 Drug Central