GPCRdb

CHEMBL110124

Agent/drug
Bioactivity

CHEMBL110124

SMILES	COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@]12CCC(=O)[C@H]3/C(=C(\C)c1ccccc1)C2
InChIKey	LDDLOXPGPQDUOX-WYNUPRQPSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	429.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	8.25	8.25	8.25	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.85	9.85	9.85	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.34	8.34	8.34	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	7.14	7.14	7.14	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	8.47	8.47	8.47	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.82	7.82	7.82	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL110124

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.