LY 156735


SMILES COc1cc2c(cc1Cl)[nH]cc2[C@H](CNC(=O)C)C
InChIKey RKHCTAKUYDTFHE-QMMMGPOBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 280.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 10.1 10.1 10.1 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 10.4 10.4 10.4 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 10.4 10.4 10.4 ChEMBL
MT1 MTR1A Human Melatonin A pKi 10.1 10.1 10.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database