LY2119620


SMILES CN1CCN(CC1)C(=O)COc1nc2sc(c(c2c(c1Cl)C)N)C(=O)NC1CC1
InChIKey TYTGOXSAAQWLPJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 437.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 4MQT 6U1N 6OIK 7T94 7T96 7V68

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 5.5 5.6 5.7 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKd 5.5 5.5 5.5 Guide to Pharmacology
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.03 5.19 5.45 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 5.45 5.45 5.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database