LY334370


SMILES CN1CCC(CC1)c1c[nH]c2c1cc(cc2)NC(=O)c1ccc(cc1)F
InChIKey MDMJLMDBRQXOOI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 Guide to Pharmacology
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKd 9.4 9.4 9.4 Guide to Pharmacology
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.68 8.73 8.8 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.62 6.77 7.08 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.37 6.53 6.86 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 PDSP Ki database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 PDSP Ki database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database