LY395756


SMILES C[C@@H]1C[C@@]([C@H]2[C@@H]1[C@@H]2C(=O)O)(N)C(=O)O
InChIKey BQVZICWQBFTOJX-QNDZYWSYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 199.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.78 6.78 6.78 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.52 6.52 6.52 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.24 6.38 6.52 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.39 6.58 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 5.12 5.12 5.12 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.47 5.66 5.98 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.4 6.8 7.2 ChEMBL