macimorelin


SMILES O=CN[C@@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](NC(=O)C(N)(C)C)Cc1c[nH]c2c1cccc2
InChIKey UJVDJAPJQWZRFR-DHIUTWEWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 6
Rotatable bonds 10
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pIC50 7.81 7.81 7.81 Guide to Pharmacology
ghrelin GHSR Human Ghrelin A pIC50 6.91 7.28 7.64 ChEMBL
ghrelin GHSR Human Ghrelin A pIC50 8.11 8.11 8.11 Drug Central