MB-28767


SMILES OC(=O)CCCCCC[C@@H]1[C@@H](/C=C/[C@H](COc2ccccc2)O)CCC1=O
InChIKey NZGFSDWJUZOAAX-KAVAACISSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 6.4 6.4 6.4 Guide to Pharmacology
EP2 PE2R2 Human Prostanoid A pKi 5.3 5.65 6.0 Guide to Pharmacology
EP3 PE2R3 Human Prostanoid A pKi 9.85 9.85 9.85 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 7.5 7.75 8.0 Guide to Pharmacology
FP PF2R Human Prostanoid A pKi 6.3 6.3 6.3 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 6.5 6.5 6.5 Guide to Pharmacology
EP1 PE2R1 Mouse Prostanoid A pKi 6.9 6.9 6.9 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 9.15 9.15 9.15 Guide to Pharmacology
EP1 PE2R1 Rat Prostanoid A pKi 6.3 6.3 6.3 Guide to Pharmacology
FP PF2R Mouse Prostanoid A pKi 6.9 6.9 6.9 Guide to Pharmacology
EP2 PE2R2 Rat Prostanoid A pKi 5.9 5.9 5.9 Guide to Pharmacology
EP4 PE2R4 Rat Prostanoid A pKi 7.6 7.6 7.6 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKi 6.3 6.3 6.3 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 9.17 9.17 9.17 PDSP Ki database
FP PF2R Mouse Prostanoid A pKi 6.91 6.91 6.91 PDSP Ki database
EP4 PE2R4 Mouse Prostanoid A pKi 6.3 6.3 6.3 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 6.38 6.38 6.38 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 9.85 9.85 9.85 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 6.01 7.0 8.0 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
FP PF2R Human Prostanoid A pKi 6.29 6.29 6.29 PDSP Ki database
IP PI2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
EP1 PE2R1 Mouse Prostanoid A pKi 6.92 6.92 6.92 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pEC50 7.75 7.75 7.75 Guide to Pharmacology
EP3 PE2R3 Rat Prostanoid A pEC50 9.26 9.26 9.26 Guide to Pharmacology