CHEMBL2443000


SMILES COc1ccccc1N1CCN(Cc2cn(CCOCCOCCF)nn2)CC1
InChIKey BGXXETBYBGTKEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 407.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Pig Adrenoceptors A pKi 6.31 6.31 6.31 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.52 4.52 4.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.29 5.29 5.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.11 5.29 5.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database