CHEMBL2443004


SMILES COc1ccccc1N1CCN(Cc2cn(-c3ccc(OCCF)cc3)nn2)CC1
InChIKey LHYAIPJNIYZFAE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Pig Adrenoceptors A pKi 6.92 6.92 6.92 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.35 4.35 4.35 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.77 4.77 4.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.75 5.28 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database