CHEMBL2443009


SMILES COc1ccccc1N1CCN(Cc2cn(CCCCCCF)nn2)CC1
InChIKey UQNPMHBOQOCPSK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Pig Adrenoceptors A pKi 6.96 6.96 6.96 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.58 4.58 4.58 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.25 6.29 6.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database