metiamide
SMILES | CNC(=S)NCCSCc1nc[nH]c1C |
InChIKey | FPBPLBWLMYGIQR-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 5 |
Molecular weight (Da) | 244.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H2 | HRH2 | Rat | Histamine | A | pKi | 5.8 | 5.8 | 5.8 | Guide to Pharmacology |
H1 | HRH1 | Rat | Histamine | A | pKi | 4.0 | 4.5 | 5.0 | PDSP Ki database |
H2 | HRH2 | Guinea pig | Histamine | A | pKi | 6.29 | 6.29 | 6.29 | PDSP Ki database |
H3 | HRH3 | Rat | Histamine | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |