mevidalen


SMILES OC[C@H]1Cc2c(cccc2[C@@H](N1C(=O)Cc1c(Cl)cccc1Cl)C)CCC(O)(C)C
InChIKey XHCSBQBBGNQINS-DOTOQJQBSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7LJC 7LJD 7CKZ 7X2F

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Mouse Dopamine A pEC50 7.21 7.21 7.21 Guide to Pharmacology
D1 DRD1 Mouse Dopamine A pEC50 7.21 7.21 7.21 ChEMBL
D1 DRD1 Human Dopamine A pEC50 7.89 8.5 8.96 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.42 5.42 5.42 ChEMBL
D1 DRD1 Human Dopamine A pEC50 8.64 8.64 8.64 Guide to Pharmacology