MK 6892


SMILES Oc1ccc(nc1)c1noc(n1)CC(C(=O)NC1=C(CCCC1)C(=O)O)(C)C
InChIKey CJHXBFSJXDUJHP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 8IHF 8JZ7 8J6R 8IJD 7XK2

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
HCA2 HCAR2 Human Hydroxycarboxylic acid A pKi 8.4 8.4 8.4 Guide to Pharmacology
HCA2 HCAR2 Human Hydroxycarboxylic acid A pKi 6.22 7.31 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
HCA2 HCAR2 Human Hydroxycarboxylic acid A pEC50 7.8 7.8 7.8 Guide to Pharmacology
HCA2 HCAR2 Rat Hydroxycarboxylic acid A pEC50 5.34 5.34 5.34 ChEMBL
HCA2 HCAR2 Mouse Hydroxycarboxylic acid A pEC50 6.62 6.62 6.62 ChEMBL
HCA2 HCAR2 Human Hydroxycarboxylic acid A pEC50 7.8 7.8 7.8 ChEMBL