cinacalcet



cinacalcet


SMILES C[C@H](c1cccc2c1cccc2)NCCCc1cccc(c1)C(F)(F)F
InChIKey VDHAWDNDOKGFTD-MRXNPFEDSA-N

Chemical Properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 357.2

Database connections

Structure pdb 7M3F 8SZF 8SZG 8SZH 8WPG 8WPU
Ligand site mutations CaS

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

cinacalcet


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Clinical Trials

Phase I 1
Phase II 1
Phase III 0
Approved Yes

Database connections

Structure pdb 7M3F 8SZF 8SZG 8SZH 8WPG 8WPU
Ligand site mutations CaS

Sankey plot

Drug Information

Target Disease Phase
Gene Protein Receptor family Ligand type Class Indication name ICD11 ATC Association score Phase Approved