CHEMBL24981


SMILES COc1ccc(Cl)cc1N1CCN(CCCNc2nccc(C(N)=O)n2)CC1
InChIKey NNPHPGSVPQWUHP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.9 7.9 7.9 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.6 8.65 8.7 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database