CHEMBL257077


SMILES CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3cccc(Cl)c3)CC2)CC1
InChIKey MHMZJEYRSGRQHH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.56 6.86 7.15 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.66 7.97 8.29 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.54 8.18 8.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.97 7.03 7.08 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.56 6.86 7.15 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 7.54 8.08 8.82 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.97 7.03 7.08 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database