CHEMBL257097


SMILES CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3cc(F)ccc3F)CC2)CC1
InChIKey NXJNUASOAQRPKJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 472.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.59 7.02 7.44 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.58 8.18 8.77 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.28 8.1 8.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 8.02 9.34 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.59 7.02 7.44 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 7.28 8.14 8.92 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.7 8.02 9.34 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database