CHEMBL257098


SMILES CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3ccccc3Cl)CC2)CC1
InChIKey LHOVFJRBCVNIQC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.43 6.92 7.41 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.32 7.64 7.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.34 7.93 8.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.06 6.77 7.48 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.43 6.92 7.41 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 7.32 7.79 8.52 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.06 6.77 7.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database