CHEMBL259656


SMILES O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1)(c1ccc(Cl)cc1Cl)O2)N1CCOCC1
InChIKey VUCKSZWMRCSPME-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 491.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 8.4 8.4 8.4 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 8.52 8.52 8.52 PDSP Ki database
CB1 CNR1 Human Cannabinoid A pKi 7.46 8.11 8.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pEC50 7.96 7.96 7.96 ChEMBL