NIBR189


SMILES COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C(=O)/C=C/C3=CC=C(C=C3)Br
InChIKey OFHXXBRBGWUOHR-NYYWCZLTSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 428.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR183 GP183 Human A orphans A pIC50 7.96 7.96 7.96 Guide to Pharmacology
GPR183 GP183 Mouse A orphans A pIC50 7.82 7.82 7.82 Guide to Pharmacology
GPR183 GP183 Mouse A orphans A pIC50 7.82 7.84 7.86 ChEMBL
GPR183 GP183 Human A orphans A pIC50 7.96 8.45 9.65 ChEMBL