CHEMBL2376484


SMILES Cc1[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc2c1C1=CCNCC1
InChIKey TVGSRQITRNMKJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 360.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 7.54 7.54 7.54 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.75 5.75 5.75 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.3 7.3 7.3 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 7.5 7.5 7.5 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.0 6.0 6.0 ChEMBL