olodaterol


SMILES COc1ccc(cc1)CC(NC[C@@H](c1cc(O)cc2c1OCC(=O)N2)O)(C)C
InChIKey COUYJEVMBVSIHV-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 8JJL

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 8.13 8.13 8.13 Drug Central
β2 ADRB2 Human Adrenoceptors A pKi 8.04 8.04 8.04 Drug Central
β3 ADRB3 Human Adrenoceptors A pKi 8.28 8.28 8.28 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pEC50 10.0 10.0 10.0 Guide to Pharmacology
β1 ADRB1 Human Adrenoceptors A pEC50 6.91 7.23 7.56 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 10.06 10.38 10.7 ChEMBL