GPCRdb

CHEMBL266647

Agent/drug
Bioactivity

CHEMBL266647

SMILES	CC(C)C[C@H](NC(=O)CCN(C)C)c1cc(Cl)ccc1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1
InChIKey	NICHJJOSEXYBED-AMGIVPHBSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	11
Molecular weight (Da)	560.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

ghrelin	GHSR	Human	Ghrelin	A	pKi	6.34	6.34	6.34	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	6.15	6.15	6.15	ChEMBL
MC₄	MC4R	Mouse	Melanocortin	A	pKi	7.75	7.75	7.75	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	8.47	8.47	8.47	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	6.22	6.22	6.22	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

ghrelin	GHSR	Human	Ghrelin	A	pEC50	6.14	6.14	6.14	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pIC50	6.03	6.03	6.03	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL266647

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.