GPCRdb

IOLOPRIDE

Agent/drug
Bioactivity

IOLOPRIDE

SMILES	CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(I)c1O
InChIKey	CANPFCFJURGKAX-JTQLQIEISA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	5
Molecular weight (Da)	404.1

Database connections

ChEMBL_compound_ids PubChem PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Pig	Dopamine	A	pKi	4.92	4.92	4.92	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	9.20	9.38	9.58	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKd	9.37	9.37	9.37	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	8.38	8.38	8.38	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.38	8.38	8.38	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.24	6.24	6.24	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Rat	Dopamine	A	pIC50	8.92	8.92	8.92	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pIC50	8.47	8.72	8.92	ChEMBL

Showing 1 to 2 of 2 entries

IOLOPRIDE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem PubChem GPCRdb

Compound is not listed as a drug.