CHEMBL271913


SMILES COc1ccc(Cl)cc1NC(=O)NC1CCC(N2CCN(c3ccccc3OC(C)C)CC2)CC1
InChIKey AVIOZEGAUFSOTR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 500.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.68 6.88 7.09 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.0 7.23 7.47 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.19 7.88 8.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.0 7.96 8.92 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.68 6.88 7.09 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 7.0 7.56 8.57 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.0 7.96 8.92 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database