CHEMBL272340


SMILES COc1ccccc1NC(=O)NC1CCC(N2CCN(c3ccccc3OC(C)C)CC2)CC1
InChIKey MVVUJPWQKLPZEE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 466.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.65 6.81 6.97 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.81 7.12 7.42 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.14 7.6 8.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.04 6.22 6.41 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.65 6.81 6.97 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 6.81 7.36 8.06 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.04 6.22 6.41 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database