CHEMBL27254


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(I)cc2)CC1
InChIKey PZTFOAIQGVVNAX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 493.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.41 8.41 8.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Green monkey Dopamine A pEC50 8.92 8.92 8.92 ChEMBL