oxytocin


SMILES None
InChIKey XNOPRXBHLZRZKH-DSZYJQQASA-N
Sequence CYIQNCPLG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7QVM 7RYC

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 6.9 7.6 8.3 Guide to Pharmacology
V1A V1AR Human Vasopressin and oxytocin A pKd 6.9 6.9 6.9 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 5.7 6.35 7.0 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKd 5.8 5.8 5.8 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 5.4 6.1 6.8 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKd 5.8 5.8 5.8 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKi 8.2 8.9 9.6 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKd 8.2 8.85 9.5 Guide to Pharmacology
V1A V1AR Rat Vasopressin and oxytocin A pKi 6.1 6.1 6.1 Guide to Pharmacology
OT OXYR Rat Vasopressin and oxytocin A pKi 8.7 8.7 8.7 Guide to Pharmacology
OT OXYR Rat Vasopressin and oxytocin A pKi 8.77 8.91 9.05 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pKi 5.75 5.75 5.75 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKd 8.17 8.17 8.17 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 8.02 8.85 9.36 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 5.46 5.63 5.81 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 6.92 7.25 7.7 ChEMBL
V1B V1BR Rat Vasopressin and oxytocin A pKi 7.4 7.4 7.4 PDSP Ki database
V1A V1AR Rat Vasopressin and oxytocin A pKi 7.23 7.29 7.34 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 6.0 6.08 6.17 PDSP Ki database
V1A V1AR Human Vasopressin and oxytocin A pKi 6.91 6.91 6.91 PDSP Ki database
V1B V1BR Human Vasopressin and oxytocin A pKi 5.75 5.75 5.75 PDSP Ki database
V2 V2R Human Vasopressin and oxytocin A pKi 5.81 5.81 5.81 PDSP Ki database
OT OXYR Human Vasopressin and oxytocin A pKi 9.15 9.23 9.3 PDSP Ki database
OT OXYR Rat Vasopressin and oxytocin A pKi 8.72 8.89 9.05 PDSP Ki database
OT OXYR Human Vasopressin and oxytocin A pKi 8.04 8.04 8.04 Drug Central
V1A V1AR Rat Vasopressin and oxytocin A pKi 8.21 8.21 8.21 Drug Central
V2 V2R Rat Vasopressin and oxytocin A pKi 8.14 8.14 8.14 Drug Central
OT OXYR Rat Vasopressin and oxytocin A pKi 8.04 8.04 8.04 Drug Central
V2 V2R Rat Vasopressin and oxytocin A pKi 7.06 7.13 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Mouse Vasopressin and oxytocin A pEC50 8.7 8.7 8.7 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pEC50 6.62 7.73 9.7 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pIC50 8.57 8.57 8.57 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pEC50 7.58 8.84 11.0 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pEC50 6.09 7.11 8.14 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pEC50 6.58 8.28 9.74 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pEC50 8.16 8.16 8.16 Drug Central
V1B V1BR Human Vasopressin and oxytocin A pEC50 8.2 8.2 8.2 Drug Central
V2 V2R Human Vasopressin and oxytocin A pEC50 8.21 8.21 8.21 Drug Central