palosuran


SMILES O=C(Nc1cc(C)nc2c1cccc2)NCCN1CCC(CC1)(O)Cc1ccccc1
InChIKey WYJCYXOCHXWTHG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Rhesus macaque Urotensin A pKi 8.4 8.4 8.4 ChEMBL
UT UR2R Human Urotensin A pKi 7.39 7.85 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Human Urotensin A pIC50 7.1 7.1 7.1 Guide to Pharmacology
UT UR2R Human Urotensin A pIC50 6.5 7.45 8.44 ChEMBL
UT UR2R Rat Urotensin A pIC50 7.77 7.77 7.77 ChEMBL