perospirone


SMILES O=C1N(CCCCN2CCN(CC2)c2nsc3c2cccc3)C(=O)[C@@H]2[C@H]1CCCC2
InChIKey FBVFZWUMDDXLLG-HDICACEKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 9.22 9.22 9.22 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 9.55 9.55 9.55 Guide to Pharmacology
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 4.74 4.74 4.74 Guide to Pharmacology
D2 DRD2 Human Dopamine A pKi 8.04 8.04 8.04 Drug Central
D3 DRD3 Human Dopamine A pKi 8.02 8.02 8.02 Drug Central
D4 DRD4 Human Dopamine A pKi 8.0 8.0 8.0 Drug Central
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.32 8.32 8.32 Drug Central
D4 DRD4 Human Dopamine A pKi 10.05 10.05 10.05 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database