CHEMBL280223


SMILES O=C(O)CCCCCCN1C(=O)CC[C@@H]1/C=C/C(O)C1(c2ccccc2)CC1
InChIKey DVDIXSPSNQPVNX-QHYGYJHXSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 4.55 4.55 4.55 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 4.7 5.09 5.48 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pEC50 6.75 6.75 6.75 ChEMBL