CHEMBL281986


SMILES CO[C@]12C=CC3(CC14CCC[C@H]4O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)[C@@H]2O5
InChIKey RLFSNZBLDVZMLA-MCRZJHBZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.16 9.16 9.16 ChEMBL
κ OPRK Human Opioid A pKi 8.98 8.98 8.98 ChEMBL
μ OPRM Human Opioid A pKi 9.49 9.49 9.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.52 9.52 9.52 ChEMBL
κ OPRK Human Opioid A pEC50 10.4 10.4 10.4 ChEMBL
μ OPRM Human Opioid A pEC50 8.55 8.55 8.55 ChEMBL